Mobility Problems and LamenessLameness (limping) and general problems moving are the most common and sometimes only clinical signs seen in dogs infected with Lyme disease. Shifting leg lameness (i.e., standing with more weight on one limb, then shifting to another limb), exercise intolerance, increased sitting or lying down, or discomfort when an affected joint is taken through range of motion from Lyme-related arthritis (joint inflammation) or muscle pain.
Lethargy (increased fatigue)Dogs infected with Lyme disease are more lethargic, which means they will act more tired instead of being awake and energetic. Lethargy occurs as a result of the immune system’s increased efforts to fight the Lyme disease bacteria through the production of antibodies and white blood cells. Body temperature elevation (hyperthermia) is often association with lethargy.
Anorexia (lack of appetite) and Digestive Tract UpsetLyme disease causes anorexia, which appears as a substantially decreased appetite or even to the point that all meals or treats may be completely refused. Anorexia can be caused by hyperthermia, arthritis , muscle pain, kidney failure, or other ailments associated with infection. In addition, dogs infected with Lyme disease may have vomiting or diarrhea.
Increased water consumption and Increased urine output
This can be caused by kidney failure from Lyme-disease. More water going in leads to increased urine output. Failing kidneys have a reduced ability to concentrate urine, and the dog will drink more water to compensate for that lack of kidney function.